Migraine is a type of headache marked by severe head pain lasting several hours or more. Migraine is an intense, often debilitating type of headache. Migraines affect as many as 24 million people in the United States, and are responsible for billions of dollars in lost work, poor job performance, and direct medical costs. Approximately 18% of women and 6% of men experience at least one migraine attack per year. More than three million women and one million men have one or more severe headaches every month. Migraines often begin in adolescence, and are rare after age 60.